ID: 999998

Recommendation from system received

GLD_R30 Immunotherapy treatment should be delayed.

Recommendation from system received

Oral corticosteroids (0.5–1 mg/kg/day prednisone equivalent) are recommended in the case of diffuse ulceration or bleeding under endoscopic evaluation, or persistent symptoms after 3 days with symptomatic treatments 6 budesonide [III,A]

Patient reported symptom

diarrhoea grade 2

Educational Intervention (GLD_R15) prescribed

Avoid very fatty food and spicy food

Recommendation from system received

Stop St. John’s wort (GLD_RM1)

Goal: Treatment of Depressive disorder

Explanation: An interaction has been found between St. John's wort and loperamide: St. John's wort inhibits the effects of loperamide. Hence St. John's wort has to be stopped

Source: FAERS

Grade of evidence: Auto generated

Recommendation from system received

Start Loperamide (GLD_R3)

Goal: Treatment of Diarrhea

Explanation: The incidence of therapy-related diarrhoea is 44-55%. A prescription for Loperamide as needed (A/N) is suggested. Patients with grade 1 or 2 diarrhoea with no other complicating signs or symptoms may be managed conservatively with oral hydration and loperamide [V, A]

Source: ESMO diarrhea GL

Grade of evidence: [V, A]

Patient reported symptom

Diarrhoea grade 1

Patient completed Insomnia Severity Index (ISI) questionnaire

Result: Severity Index value is 17 which indicates “clinical insomnia moderate intensity”

Title

Fitbit band connected

Capsule activated

Sleep

Treatment prescribed

St. John’s-wort 300 mg, daily, for 28 days

Treatment prescribed

Nivolumab 240 mg every two weeks, Sunitinib 50 mg, daily, for 28 days

Title

Profile created